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6-hydroxy-4-methoxy-5-benzofuranacrylic Acid, Gamma-lactone


Properties
Product Name 6-Hydroxy-4-methoxy-5-benzofuranacrylic acid, gamma-lactone
Cas Number 142489-65-8
Formula C11H8O5
Molar Mass 220.18
Property 1 Appearance: Solid
Property 2 Color: White to off-white
Property 3 Melting Point: Not available
Property 4 Solubility: Soluble in organic solvents
Property 5 Boiling Point: Not available
Property 6 Density: Not available
Property 7 Refractive Index: Not available
Property 8 Flash Point: Not available
Property 9 Stability: Stable under normal conditions
Property 10 Hazard Statements: Not available
FAQ

What are the main applications of 6-Hydroxy-4-methoxy-5-benzofuranacrylic acid, gamma-lactone?

6 - Hydroxy - 4 - methoxy - 5 - benzofuranacrylic acid, gamma - lactone has several main applications.There are several applications for 6 - Hydroxy- 4 – methoxy- 5 – benzofuranacrylic acids, gamma-lactone.
One of its significant applications is in the field of pharmaceuticals.Pharmaceuticals is one of its most important applications. It may serve as a key intermediate in the synthesis of certain drugs.It can be used as a key ingredient in the synthesis for certain drugs. Its unique chemical structure can contribute to the development of compounds with specific biological activities.Its unique chemistry can help to develop compounds with specific biological properties. For example, it could potentially be involved in the creation of drugs targeting particular biochemical pathways in the human body.It could, for example, be used to create drugs that target specific biochemical pathways within the human body. By incorporating this compound into the synthetic route, researchers can design molecules that interact with specific receptors or enzymes, aiming to treat various diseases such as inflammatory disorders or certain types of cancers.Researchers can create molecules that interact with receptors or enzymes by incorporating this compound in the synthetic route. This could be used to treat diseases such as inflammatory disorders and certain types of cancer.

In the area of natural product synthesis, this lactone is of great value.This lactone is of great importance in the field of natural product synthesis. Many natural products with important biological functions possess similar structural features.Many natural products that have important biological functions share similar structural features. Scientists can use 6 - Hydroxy - 4 - methoxy - 5 - benzofuranacrylic acid, gamma - lactone as a starting point or a building block to mimic and synthesize these natural products in the laboratory.Scientists can use 6- Hydroxy- 4- methoxy- 5- benzofuranacrylic acids, gamma-lactone as a building-block or starting point to mimic and synthesize natural products in the lab. This not only helps in understanding the structure - activity relationships of natural substances but also enables the production of larger quantities of these potentially beneficial compounds for further research and possible therapeutic applications.This not only helps to understand the structure-activity relationships of natural substances, but also allows for the production of larger amounts of these potentially beneficial compound for further research and therapeutic applications.

It also has potential applications in the realm of materials science.It has potential applications within the field of materials science. Due to its chemical properties, it could be used to modify the surface properties of materials.Its chemical properties could be used to modify surface properties of materials. For instance, when incorporated into polymers, it might enhance the polymer's solubility, reactivity, or its ability to interact with other substances.When incorporated into polymers it could enhance the polymer’s solubility or reactivity, as well as its ability to interact and interact with other substances. This can lead to the development of new types of functional materials, such as coatings that have better adhesion, or polymers with improved biocompatibility, which are useful in medical device manufacturing or in the production of environmentally friendly packaging materials.This can lead to new types of functional material, such as coatings with better adhesion or polymers that are biocompatible, which is useful in the manufacture of medical devices or environmentally friendly packaging materials.

Furthermore, in the field of organic synthesis research, it serves as an important model compound.It is also a model compound in the field of research on organic synthesis. Chemists can study various chemical reactions using this lactone, such as oxidation, reduction, and substitution reactions.Chemists are able to study a variety of chemical reactions, including oxidation, substitution, and reduction reactions, using this lactone. These studies help in the development of new synthetic methodologies and the optimization of existing ones.These studies can be used to develop new synthetic methods and optimize existing ones. Understanding how this compound reacts under different conditions can expand the toolkit of organic chemists, enabling them to create more complex and useful organic molecules for a wide range of applications in different industries.Understanding how this compound behaves under different conditions will allow organic chemists to expand their toolkit, allowing them to create more complex organic molecules that can be used in a variety of industries.

What are the properties of 6-Hydroxy-4-methoxy-5-benzofuranacrylic acid, gamma-lactone?

6 - Hydroxy - 4 - methoxy - 5 - benzofuranacrylic acid, gamma - lactone likely has several notable properties.The gamma-lactone, 6 - Hydroxy- 4 – methoxy- 5 – benzofuranacrylic acids, likely has several notable characteristics.
In terms of its physical properties, it is probably a solid at room temperature due to the presence of its relatively complex molecular structure with a benzofuran ring, a lactone ring, and other functional groups.It is likely a solid due to its complex molecular structure, which includes a benzofuran, a lactone, and other functional groups. These rings and groups contribute to strong intermolecular forces such as van der Waals forces and potentially hydrogen bonding.These rings and functional groups contribute to strong intermolecular interactions such as van der Waals and hydrogen bonding. The presence of the methoxy group (-OCH3) and the hydroxy group (-OH) on the benzofuran ring can influence its solubility.The presence of a methoxy group on the benzofuran rings (-OCH3) or hydroxy group (OH) can affect its solubility. The hydroxy group can participate in hydrogen bonding with polar solvents like water, but the overall hydrophobic nature of the benzofuran and lactone rings may limit its solubility in water.The hydroxyl group can hydrogen bond with polar solvents such as water, but its overall hydrophobicity may limit its solubility. It may be more soluble in polar organic solvents such as ethanol or acetone, which can interact with both the polar and non - polar parts of the molecule.It may be more soluble with polar organic solvents like acetone or ethanol, which can interact both the non-polar and polar parts of molecule.

Chemically, the lactone ring is a reactive site.The lactone ring has a reactive property. Lactones can undergo hydrolysis reactions in the presence of water and an appropriate catalyst, such as an acid or a base.Lactones can undergo hydrolysis in the presence of an appropriate catalyst such as an acid, or base. In acidic conditions, the lactone ring can be protonated, making it more susceptible to nucleophilic attack by water molecules, leading to the opening of the ring and the formation of the corresponding carboxylic acid and alcohol groups.In acidic conditions the lactone ring is protonated to make it more susceptible to nucleophilic attacks by water molecules. This leads to the opening of ring, and formation of carboxylic acid or alcohol groups. In basic conditions, hydroxide ions can act as the nucleophile to open the lactone ring.In basic conditions, the hydroxide ions act as a nucleophile and open the lactone rings.

The hydroxy group on the benzofuran ring can also be involved in chemical reactions.The hydroxyl group on the benzofuran rings can also be involved with chemical reactions. It can be easily acetylated or alkylated.It is easily acetylated and alkylated. For example, treatment with an acyl chloride or an alkyl halide in the presence of a base can lead to the formation of the corresponding esters or ethers respectively.Treatment with an acyl halide or an alkyl chloride in presence of a basic can lead to the respective esters or ethers.

The double bond in the acrylic acid part of the molecule (even though it is part of the lactone structure) can potentially participate in addition reactions.The double bond in this part of molecule (even if it is part lactone structure) could potentially participate in addition reaction. For instance, it could react with electrophiles in electrophilic addition reactions.It could, for example, react with electrophiles during electrophilic addition. This double bond also contributes to the molecule's potential for conjugation with the benzofuran ring system, which can affect its electronic properties and spectroscopic behavior.This double bond contributes to the molecule’s ability to conjugate with the benzofuran rings system, which can influence its electronic properties and spectrum.

From a spectroscopic perspective, in the infrared spectrum, characteristic absorption bands can be expected.In the infrared spectrum characteristic absorption bands are expected. The lactone carbonyl group will show a strong absorption in the region around 1700 - 1750 cm - 1, corresponding to the C=O stretching vibration.The lactone carbonyl will exhibit a strong absorption around 1700-1750 cm-1, which corresponds to the C=O vibration. The hydroxy group will exhibit a broad absorption around 3200 - 3600 cm - 1 due to the O - H stretching vibration.The hydroxyl group will show a broad absorption in the region around 3200 – 3600 cm – 1 due to O -H stretching vibration. The aromatic ring in the benzofuran moiety will show characteristic absorptions in the regions associated with C - H stretching and bending vibrations of aromatic compounds.The aromatic ring of the benzofuran moiety shows characteristic absorptions around the regions associated with C-H stretching and bending vibrations. In the nuclear magnetic resonance spectra, the different types of hydrogen atoms in the molecule will give distinct signals, allowing for the determination of the molecular structure and the relative positions of the functional groups.The different types of hydrogen in the molecule give distinct signals. This allows the determination of the molten structure and the relative positions between the functional groups.

How is 6-Hydroxy-4-methoxy-5-benzofuranacrylic acid, gamma-lactone synthesized?

6 - Hydroxy - 4 - methoxy - 5 - benzofuranacrylic acid, gamma - lactone can be synthesized through a multi - step process.A multi-step process can be used to synthesize 6 – Hydroxy – 4 – methoxy – 5 - benzofuranacrylic acids, gamma-lactone.
One possible synthetic route might start with a suitable starting material, perhaps a benzene derivative with appropriate functional groups.A possible route to a synthetic product could begin with a starting material that is suitable, such as a benzene-derivative with functional groups that are appropriate. For example, a compound with a methoxy group and a hydroxyl - adjacent position on the benzene ring could be used.A compound with a methoxy-group and a hydroxyl-near position on the benzene rings could be used.

First step: Preparation of the benzofuran core.First step: preparation of the benzofuran ring. The starting benzene derivative could be reacted with reagents to form the benzofuran ring.The benzene derivative used as a starting point could be treated with reagents in order to form the benzofuran rings. This might involve cyclization reactions.This could involve cyclization. For instance, if there is a side - chain with a suitable functional group arrangement, intramolecular cyclization in the presence of appropriate catalysts (such as acids or bases depending on the reaction mechanism) can lead to the formation of the benzofuran structure.If there is a side-chain with a suitable functional arrangement, intramolecular cycling in the presence or appropriate catalysts can lead to benzofuran formation.

Second step: Introduction of the acrylic acid moiety.Second step: introduction of the acrylic acid moiety. After obtaining the benzofuran compound, the next step is to attach the acrylic acid group.The next step after obtaining the benzofuran is to attach the group of acrylic acid. This can be achieved through a series of reactions.This can be done through a series reactions. One common approach could be a Wittig - type reaction.A Wittig-type reaction is a common method. A phosphonium ylide prepared from an appropriate alkyl halide can react with a carbonyl - containing benzofuran derivative.A phosphonium-containing benzofuran derivative can react with the ylide of phosphonium prepared from an alkyl halide. The reaction of the ylide with the carbonyl group leads to the formation of a double bond, thus introducing the acrylic acid - like structure.The reaction between the ylide and the carbonyl group results in the formation of a two-bond structure, which is similar to acrylic acid.

Third step: Lactonization.Third step: lactonization. To form the gamma - lactone, the carboxylic acid group of the 6 - Hydroxy - 4 - methoxy - 5 - benzofuranacrylic acid needs to cyclize with the adjacent hydroxyl group.To form gamma-lactone, the carboxylic group of the 6 – Hydroxy – 4 – methoxy -5 - benzofuranacrylic acids must cyclize with its adjacent hydroxyl group. This can be accomplished under acidic or basic conditions.This can be done under acidic or base conditions. In acidic conditions, the hydroxyl group can attack the carbonyl carbon of the carboxylic acid group, with the elimination of water, leading to the formation of the gamma - lactone ring.In acidic conditions the hydroxyl group attacks the carbonyl carbon in the carboxylic group, resulting in the elimination of water. This leads to the formation of a gamma-lactone ring. In basic conditions, the carboxylate anion can react intramolecularly with the protonated hydroxyl group (after appropriate activation steps) to form the lactone.In basic conditions, carboxylate anion reacts intramolecularly (after appropriate activation) with the protonated group of the hydroxyl to form lactone.

Throughout the synthesis, careful control of reaction conditions such as temperature, reaction time, and reagent stoichiometry is crucial.It is important to control the reaction conditions, such as temperature, time, and reagent ratio, throughout the synthesis. Purification steps like column chromatography or recrystallization are also necessary after each major reaction step to isolate the pure intermediate products and finally obtain the desired 6 - Hydroxy - 4 - methoxy - 5 - benzofuranacrylic acid, gamma - lactone in good yield and purity.Purification steps such as column chromatography and recrystallization may also be required after each major step of the reaction to isolate the pure products and obtain the desired 6- Hydroxy-4-methoxy-5-benzofuranacrylic Acid, gamma-lactone with good yield and purity.

What are the safety precautions when handling 6-Hydroxy-4-methoxy-5-benzofuranacrylic acid, gamma-lactone?

6 - Hydroxy - 4 - methoxy - 5 - benzofuranacrylic acid, gamma - lactone is a chemical compound.A chemical compound is 6 – Hydroxy – 4 – Methoxy – 5 ­ benzofuranacrylic Acid, Gamma ­ Lactone. When handling it, several safety precautions should be observed.It is important to take safety precautions when handling this chemical compound.
Firstly, personal protective equipment is crucial.Personal protective equipment is essential. Wear appropriate laboratory coats or work clothes to prevent the chemical from coming into contact with your regular clothing.Wear the appropriate laboratory coats or clothing to protect your clothing from contact with the chemical. This helps avoid potential long - term exposure and reduces the risk of spreading the chemical outside the work area.This will help to avoid long-term exposure and reduce the risk of spreading chemicals outside the work area. Safety goggles are essential to protect your eyes from any splashes.Safety goggles will protect your eyes against any splashes. Even a small amount of this compound getting into the eyes could cause irritation, damage to the cornea, or other serious eye problems.Even a small amount could cause irritation or damage to the cornea. Gloves made of a suitable material, such as nitrile gloves, should be worn.Wear gloves made from a suitable material such as nitrile. This is to protect your hands from direct contact, which could lead to skin absorption, irritation, or allergic reactions.This is to protect you hands from direct contact that could cause skin absorption, irritation or allergic reactions.

Secondly, ensure proper ventilation in the handling area.Second, make sure that the area where you are handling the product is properly ventilated. If possible, work in a fume hood.If possible, use a fume-hood. This will help to remove any potentially harmful vapors that may be released during handling.This will help remove any potentially dangerous vapors which may be released when handling. Chemical vapors can be inhaled, which may cause respiratory problems, including irritation of the nose, throat, and lungs.Inhaling chemical vapors may cause respiratory problems including irritation of the throat, nose, and lungs. Inadequate ventilation can also lead to the build - up of vapors, increasing the risk of fire or explosion in some cases, although specific information regarding the flammability of this compound should be verified.Inadequate ventilation may also cause vapors to build up, increasing the risk for fire or explosion.

Thirdly, be careful during storage.Thirdly, take care when storing. Store 6 - Hydroxy - 4 - methoxy - 5 - benzofuranacrylic acid, gamma - lactone in a cool, dry place away from sources of heat, ignition, and incompatible substances.Store 6 – Hydroxy – 4 – methoxy -5 - benzofuranacrylic acids, gamma-lactone in a dry, cool place away from heat sources, ignition and incompatible substances. Chemicals can react with each other, sometimes violently, if stored incorrectly.If stored incorrectly, chemicals can react violently with each other. Check the Material Safety Data Sheet (MSDS) for information on substances that it may react with, such as strong acids, bases, or oxidizing agents.Check the Material Safety Data Sheets (MSDS) to find out what substances it may react with.

Fourthly, in case of accidental exposure, know the proper first - aid procedures.In the event of an accidental exposure, you should know how to administer first aid. If it comes into contact with the skin, immediately rinse the affected area with plenty of water for at least 15 minutes.If it comes in contact with your skin, rinse the affected area immediately with plenty of water. This should last at least 15 minutes. Remove any contaminated clothing.Remove all contaminated clothing. If it gets into the eyes, rinse thoroughly with water for an extended period and seek immediate medical attention.If it gets in the eyes, rinse with water for a long time and seek immediate medical care. In case of inhalation, move to an area with fresh air and get medical help if symptoms such as coughing or difficulty breathing occur.If you inhale the substance, get medical attention if symptoms like coughing or difficulty breathing appear. If swallowed, do not induce vomiting unless specifically instructed by a medical professional, and seek emergency medical treatment right away.If the substance is swallowed, you should not induce vomiting without the specific instructions of a medical professional. Seek immediate medical attention if symptoms such as coughing or difficulty breathing occur.

Finally, always follow good laboratory practices.Always follow good laboratory practice. Keep the work area clean and organized.Keep the area where you work clean and well-organized. Do not eat, drink, or smoke in the area where the chemical is being handled.Avoid eating, drinking, or smoking in the area where chemicals are being handled. This reduces the risk of accidentally ingesting the compound.This will reduce the risk of accidentally ingesting a compound. Also, ensure that all equipment used for handling is clean and in good working condition to prevent spills and other accidents.To prevent spills, make sure that all handling equipment is clean and in working order.

Where can I find 6-Hydroxy-4-methoxy-5-benzofuranacrylic acid, gamma-lactone for purchase?

6 - Hydroxy - 4 - methoxy - 5 - benzofuranacrylic acid, gamma - lactone is a relatively specialized chemical compound.This chemical compound is relatively specialized. Here are some common ways to find it for purchase.Here are some ways to purchase it.
1. Chemical suppliersChemical suppliers
Many large - scale chemical suppliers deal with a wide variety of organic compounds.Many large-scale chemical suppliers deal in a variety of organic compounds. Companies like Sigma - Aldrich (now part of Merck), Thermo Fisher Scientific, and Alfa Aesar are well - known in the chemical industry.Chemical companies like Sigma - Aldrich, Thermo Fisher Scientific and Alfa Aesar have a good reputation. They have extensive catalogs that may include this particular compound.These companies may have a large catalog that includes this compound. You can visit their official websites, use their search functions to look for the specific chemical by its name or chemical formula.You can search their official websites using their search function to find the chemical by name or chemical formula. These suppliers usually offer high - quality products with detailed documentation about purity, handling, and safety information.These suppliers offer high-quality products with detailed documentation on purity, handling and safety. However, their prices might be relatively high, especially for small - quantity purchases, and they often require proper registration as a researcher, business, or educational institution.Prices can be high, particularly for small-quantity purchases. They also require registration as a business, educational institution, or researcher.

2. Online chemical marketplacesOnline chemical marketplaces
There are online platforms that aggregate chemical products from multiple suppliers.Online platforms aggregate chemical products from multiple suppliers. Websites such as Alibaba Chemicals or ChemNet can be useful.Websites like Alibaba Chemicals or ChemNet are useful. On these platforms, you can find both domestic and international suppliers.These platforms allow you to find both domestic and foreign suppliers. The advantage is that you can compare prices from different sources.You can compare prices between different sources, which is a great advantage. However, you need to be cautious as the quality of products may vary.You should be careful as the quality of the products can vary. It's essential to check the supplier's reputation, customer reviews if available, and ask for product samples and certificates of analysis before making a large - scale purchase.Before making a large-scale purchase, it's important to check the supplier, their reputation, and customer reviews, if they are available. You can also ask for samples of products and certificates of analyses.

3. Specialty chemical manufacturersSpecialty chemical manufacturers
Some companies focus on manufacturing specialty chemicals.Some companies concentrate on manufacturing specialty chemicals. These manufacturers may produce 6 - Hydroxy - 4 - methoxy - 5 - benzofuranacrylic acid, gamma - lactone as part of their product line.As part of their product range, these manufacturers may produce 6- Hydroxy- 4- methoxy- 5- benzofuranacrylic acids, gamma-lactone. You can identify them through industry directories, trade shows, or by reaching out to chemical industry associations.You can find them in industry directories, at trade shows, and by contacting chemical industry associations. Contacting these specialty manufacturers directly may give you more flexibility in terms of quantity, customization, and price negotiation.Directly contacting these specialty manufacturers may give you greater flexibility in terms quantity, customization and price negotiation. They may also be more likely to work with you if you have specific requirements for the product, such as a particular purity level or packaging.They may be more willing to work with your specific requirements, such as a certain purity level or packaging.

4. Research institutions and universities4.
Sometimes, research institutions or universities may have surplus chemicals or may be able to direct you to sources.Some research institutions or universities have excess chemicals or can direct you to sources. You can try reaching out to their chemistry departments, research labs, or procurement offices.You can contact their chemistry departments or research labs. They may know of local suppliers or researchers who have access to the compound.They may have local suppliers or researchers with access to the compound. Additionally, they might be interested in collaborating on the use of the chemical if your needs align with their research interests.They may also be interested in collaborating with you on the use of a chemical if their research interests align with yours. This could potentially lead to cost - sharing or other beneficial arrangements.This could lead to cost-sharing or other beneficial arrangements.